Absolutly not. You should awlays apply make up to freshly cleaned and moisturized skin. Just be sure not to over moisturize. Make up companies have convinced the public that we need to moisturize every square inch of us. Not true. Use a good none clogging mositurizer on dry patches. I also like to use a good eye lotion. I like Olay Regenerist Eye Lifting Serum. I don't know about the lifting part, but it is an excelent mositurizer and contains some perilized pigment to make the eye area look lighter. (I have issues with dark circles.) It feels really silky going on and provides a good base for eye makeup.